Definition

1. Noun:
   • A coagulation factor: "Factor IX" is a specific protein in the blood plasma that is essential for the normal clotting of blood. It is one of several substances, known as clotting factors, that work in a sequence to form a blood clot and stop bleeding.
   • Associated with hemophilia B: A deficiency or functional absence of this factor is the cause of the inherited bleeding disorder known as hemophilia B (also called Christmas disease).

Usage Examples

• Noun:
  • The patient's prolonged bleeding time was due to a deficiency in Factor IX.
  • Hemophilia B is treated by intravenous infusion of concentrated Factor IX.
  • The gene responsible for producing Factor IX is located on the X chromosome.

Advanced Usage

• "Factor IX complex": A therapeutic concentrate containing Factor IX along with other clotting factors, used in treatment.
  • The surgeon ordered a Factor IX complex prior to the procedure to minimize bleeding risk.
• "Factor IX activity": A measurement from a blood test that determines how well Factor IX is functioning.
  • His Factor IX activity level was less than 1% of normal, indicating severe hemophilia B.

Variants and Related Words

• Christmas factor: An alternative name for Factor IX.
• Coagulation factor IX: The full technical term.
• FIX: A common abbreviation used in medical literature.
• Hemophilia B: The condition caused by Factor IX deficiency.
• Factor VIII: Another crucial clotting factor, whose deficiency causes hemophilia A.

Synonyms

• Plasma thromboplastin component (PTC): An older synonym for Factor IX.
• Antihemophilic factor B: Another historical name emphasizing its role in preventing hemophilia B.

Related Phrases

• Factor IX deficiency: The specific lack of the factor, which is hemophilia B.
  • The diagnosis was confirmed as Factor IX deficiency.
• Recombinant Factor IX: A genetically engineered version of the clotting factor used in therapy.
  • The patient receives prophylactic injections of recombinant Factor IX.

Noun

1. coagulation factor whose absence is associated with hemophilia B